Published May 20, 2008 (Exract from Business Times)
Sihuan gearing up for forays overseas
By OH BOON PING

SIHUAN Pharmaceutical Holdings hopes to stretch its business tentacles overseas with a newly acquired drug research firm in China. In an interview with BT, executive chairman Che Fengsheng said the new subsidiary - Shandong R&D Company - already has collaborations with partners in the United States and Japan, and this will help the parent penetrate these markets.

Dr Che: Sihuan's building blocks include increasing product range and deepening customer reach
Shandong R&D joined Sihuan's fold recently when the latter paid some 62.5 million yuan (S$12.3 million) for a 60 per cent stake in Shandong R&D.

Like Sihuan Pharmaceutical, Shandong R&D specialises in cardiovascular-related and anti-infection drugs - it screens, designs, matches chemical compounds and analyses drug efficacy. Research at the firm focuses primarily on replicating successful existing drugs by modifying their structure but preserving their efficacy.

'As the original drugs are already widely accepted in the West, the success rate of the 'Me Too' drugs is likely to be high too,' said Dr Che. To date, Shandong R&D has filed more than 300 Chinese or international patents.

Within China, Sihuan Pharmaceutical has launched 19 CV drugs. Of note is its proprietary Kelinao, which is now available in 27 provinces and has a hospital penetration rate of 8 per cent. Between 2004 and 2007, sales of Kelinao grew at a compound annual rate of 89 per cent.

Thanks to Kelinao's strong contribution, Sihuan Pharmaceutical reported a 98 per cent jump in net profit to 179.3 million yuan, while sales jumped 77 per cent for the year ended Dec 31, 2007.
For the first quarter ended March 31, 2008, the company posted a 66 per cent rise in net profit to 53.1 million yuan on a 115 per cent rise in sales.

It has since developed a new derivative of Kelinao called Anjieli, which has a drug lower content and caters to patients that require smaller doses but more regularly. Its other drugs include Chuanqing, which is used for less acute stages of CV diseases, and Naloxone.

Dr Che said the building blocks of his company include increasing product range and deepening customer reach. To achieve these goals, the company is committed to spending 15-20 per cent of annual revenue on research and development, and now has more than over 70 drugs under development.

Management aims to grow its presence in domestic markets such as Liaoning and Hubei - provinces where penetration is low. And to foster greater understanding of its drugs, more seminars may be organised for doctors at hospitals.
Rising incidence of CV diseases

Looking ahead, Dr Che is upbeat, citing 20 per cent annual growth in drug sales in China over the past few years.

Also, the country has seen a rising incidence of CV diseases due to changes in diet, a faster pace of life, greater work pressure and an ageing population. These factors will drive demand for CV-related drugs.

Sihuan Pharmaceutical is also open to growth through acquisition and buying product rights. It said recently that it will acquire 45 per cent of Beijing's largest privately owned pharmaceutical products distribution company for 50.7 million yuan. Beijing Purenhong Pharmaceutical Co distributes various products, in particular specialised medicines, on behalf of major Chinese and international pharmaceutical companies to 130 major hospitals in Beijing.

In a report, DMG & Partners noted that Sihuan recently obtained approval to sell Aogan, a drug used to treat brain cell damage, saying: 'This will broaden and enhance Sihuan's product portfolio and allow it to further establish its presence in China. Aogan can be paired together with its existing products to treat brain cell damage.'

'Management expects sales of this drug to commence in H208, with strong revenue contribution accruing to the group from FY09 onwards,' it added.

The research house also believes Sihuan's stake in Shandong R&D will enhance Sihuan's edge in R&D and 'open up opportunities for Sihuan to break into the international scene'.

DMG noted that the Chinese government is introducing initiatives to transform the country's pharmaceutical industry, and that consolidation among pharmaceutical firms is expected to take place. 'This will result in a competitive operating environment for the industry,' said DMG. 'However, we believe Sihuan is positioned for growth, despite the expected challenges, given its expanding distribution network and R&D capabilities.'

So lovely and touching......

*********** Story 1 ************

A girl and a boy were on a motorcycle, speeding through the night.
They loved each other a lot.....
Girl: “slow down a little... I'm scared...”
Boy: "No, it's so fun...”
Girl: "please. It’s so scary...”
Boy: "Then say that you love me...”
Girl: "Fine. I love you. Can you slow down now?"
Boy: "Give me a big hug...”
The girl gave him a big hug.
Girl: "Now can you slow down?"
Boy: "Can you take off my helmet and put it on? It's uncomfortable and it's bothering me while I ride."

The next day, there was a story in the newspaper. A motorcycle had crashed into a building because its brakes were broken. There were two people on the motorcycle, of which one died, and the other had survived...The guy knew that the brakes were broken. He didn't want to let the girl know, because he knew that the girl would have gotten scared. Instead, he was told the last time that she loved him, got a hug from her, put his helmet on her so that she can live, and die himself...

Once in a while, Right in the middle of an ordinary life, Love gives us a fairy tale...

Message "Life consists not in holding good cards but in playing those you hold well"

************** Story 2 **************

Nurse: "It was a busy morning, approximately 8:30 am , when an elderly gentleman, in his 80's, presented to have sutures (stitches) removed from his thumb.

He stated that he was in a hurry as he had an appointment at 9:00 am . I (nurse) took his vital signs and had him take a seat, knowing it would be over an hour before someone would to able to see him.

I saw him looking at his watch and decided, since I was not busy with another patient, I would evaluate his wound. On exam it was well healed, so I talked to one of the doctors, got the needed supplies to remove his sutures and redress his wound.

While taking care of his wound, we began to engage in conversation. Asked him if he had a doctor's appointment this morning somewhere else, as he was in such a hurry. The gentleman told me no, that he needed to go to the nursing home to eat breakfast with his wife.

I then inquired as to her health. He told me that she had been there for a while and that she was a victim of Alzheimer Disease.

As we talked, and I finished dressing his wound, I asked if she would be worried if he was a bit late. He replied that she no longer knew who he was, that she had not recognized him in five years now.

I was surprised, and asked him. "And you are still going every morning, even though she doesn't know who you are?" He smiled as he patted my hand and said. "She doesn't know me, but I still know who she is."

I had to hold back tears as he left, I had goose bumps on my arm, and thought, "That is the kind of love I want in my life."

True love is neither physical, nor romantic. True love is an acceptance of all that is, has been, will be, and will not be.

Good friends are like stars...You don't always see them, but you always know they're there

************ STORY 3************

The passengers on the bus watched sympathetically as the attractive young woman with the white cane made her way carefully up the steps. She paid the driver and, using her hands to feel the location of the seats, walked down the aisle and found the seat he'd told her was empty. Then she's settled in, placed her briefcase on her lap and rested her cane against her leg.

It had been a year since Susan became blind. Due to a medical misdiagnosis she had been rendered sightless, and she was suddenly thrown into a world of darkness, anger, frustration and self-pity. 'How could this have happened to me?' she would plead, her heart knotted with anger. But no matter how much she cried or ranted or prayed, she knew the painful truth, her sight was never going to return. A cloud of depression hung over Susan's once optimistic spirit. All she had to cling to was her husband Mark.

Mark was an Air Force officer and he loved Susan with all his heart. When she first lost her sight, he watched her sink into despair and was determined to help his wife gain the strength she needed to become independent again.

Finally, Susan felt ready to return to her job, but how would she get there? She used to take the bus, but was now too frightened to get around the city by herself. Mark volunteered to drive her to work each day, even though they worked at opposite ends of the city. At first, this comforted Susan and fulfilled Mark's need to protect his sightless wife who was so insecure about performing the slightest task. Soon, however Mark realized that this arrangement wasn't working - it was hectic, and costly.

Susan is going to have to start taking the bus again, he admitted to himself. But just the thought of mentioning it to her made him cringe. She was still so fragile, so angry. How would she react? Just as Mark predicted, Susan was horrified at the idea of taking the bus again. "I'm blind!" she responded bitterly. "How am I supposed to know where I'm going? I feel like you're abandoning me."

Mark's heart broke but he knew what had to be done. He promised Susan that each day he would ride the bus with her until she got the hang of it.

And that is exactly what happened. For two solid weeks, Mark, military uniform and all accompanied Susan to and from work each day. He taught her how to rely on her other senses to determine where she was and how to adapt to her new environment. He helped her befriend the bus drivers who could watch out for her, and save her a seat. Each morning they made the journey together, and Mark would take a cab back to his office.

Although this routine was even more costly and exhausting than the previous one, Mark knew it was only a matter of time before Susan would be able to ride the bus on her own. Finally, Susan decided that she was ready to try the trip on her own. Monday morning arrived, and before she left, she threw her arms around Mark, her temporary bus riding companion, her husband, and her best friend. Her eyes filled with tears of gratitude for his loyalty, his patience, his love. She said good-bye, and for the first time, they went their separate ways. Monday, Tuesday, Wednesday, Thursday.... Each day on her own went perfectly, and Susan had never felt better.

On Friday morning, Susan took the bus to work as usual. As she was paying for her fare to exit the bus, the driver said, "Boy, I sure envy you." Susan wasn't sure if the driver was speaking to her or not. After all, who on earth would ever envy a blind woman who had struggled just to find the courage to live for the past year? "Why do you envy me?"

The driver responded, "It must feel so good to be taken care of and protected like you are." Susan had no idea what the driver was talking about, "What do you mean?" The driver said, "You know, every morning for the past week, a fine looking gentleman in a military uniform has been standing across the corner watching you when you get off the bus. He makes sure you cross the street safely and he watches you until you enter your office building. Then he blows you a kiss, gives you a little salute and walks away. You are one lucky lady."

Tears of happiness poured down Susan's cheeks. For although she couldn't see him, she had always felt Mark's presence. She was blessed, so blessed, for he had given her a gift more powerful than sight, a gift she didn't need to see to believe - the gift of love that can bring light where there had been darkness.

"You don't love a woman because she is beautiful, but she is beautiful because you love her..."

So if you love someone be faithful to that person.

*************STORY 4*************

From the very beginning, girl's family objected strongly on her dating this guy, saying that it has got to do with family background, & that the girl will have to suffer for the rest of her life if she were to be with him.

Due to family's pressure, the couple quarreled very often. Though the girl loved the guy deeply, she always asked him: "How deep is your love for me?" As the guy is not good with his words, this often caused the girl to be very upset. With that & the family's pressure, the girl often vents her anger on him. As for him, he only endured it in silence.

After a couple of years, the guy finally graduated & decided to further his studies overseas. Before leaving, he proposed to the girl:

"I'm not very good with words. But all I know is that I love you. If you allow me, I will take care of you for the rest of my life. As for your family, I'll try my best to talk them round. Will you marry me?" The girl agreed, & with the guy's determination, the family finally gave in & agreed to let them get married. So before he left, they got engaged. The girl went out to the working society, whereas the guy was overseas, continuing his studies. They sent their love through emails & phone calls. Though it was hard, but both never thought of giving up.

One day, while the girl was on her way to work, she was knocked down by a car that lost control. When she woke up, she saw her parents beside her bed. She realized that she was badly injured. Seeing her mum crying, she wanted to comfort her. But she realized that all that could come out of her mouth was just a sigh. She had lost her voice....

The doctor says that the impact on her brain has caused her to lose her voice. Listening to her parents' comfort, but with nothing coming out from her, she broke down. During the stay in hospital, besides silence cry, it’s still just silence cry that accompanied her. Upon reaching home, everything seems to be the same. Except for the ringing tone of the phone. This pierced into her heart every time it rang.

She does not wish to let the guy know & not wanting to be a burden to him, she wrote a letter to him saying that she does not wish to wait any longer.

With that, she sent the ring back to him. In return, the guy sent millions & millions of reply, countless of phone calls, all the girl could do, besides crying, is still crying.... The parents decided to move away, hoping that she could eventually forget everything & be happy.

With a new environment, the girl learns sign language & started a new life. Telling her everyday that she must forget the guy. One day, her friend came & told her that he's back. She asked her friend not to let him know what happened to her. Since then, there wasn't anymore news of him.

A year has passed & her friend came with an envelope, containing an invitation card for the guy's wedding. The girl was shattered. When she opens the letter, she saw her name in it instead. When she was about to ask her friend what's going on, she saw the guy standing in front of her.

He used sign language to tell her "I've spent a year to learn sign language. Just to let you know that I've not forgotten our promise. Let me have the chance to be your voice. I Love You." With that, he slipped the ring back into her finger. The girl finally smiled.

Treat every relationship as if it's the last one, then you'll know how to give. Treat every moment as is it's the last day, and then you'll know how to treasure.

Treasure what you have right now, or else you will regret one day...

************ STORY 5 **************

After 21 years of marriage, I discovered a new way of keeping alive the spark of love. A little while ago I had started to go out with another woman. It was really my wife's idea.

"I know that you love her," she said one day, taking me by surprise. "But I love YOU," I protested.

"I know, but you also love her.” The other woman that my wife wanted me to visit was my mother, who has been a widow for 19 years, but the demands of my work and my three children had made it possible to visit her only occasionally. That night I called to invite her to go out for dinner and a movie. "What's wrong, are you well?" she asked. My mother is the type of woman who suspects that a late night call or a surprise invitation is a sign of bad news.

"I thought that it would be pleasant to pass some time with you," I responded.

"Just the two of us."

She thought about it for a moment then said "I would like that very much."

That Friday after work, as I drove over to pick her up I was a bit nervous.

When I arrived at her house, I noticed that she, too, seemed to be nervous about our date. She waited in the door with her coat on.

She had curled her hair and was wearing the dress that she had worn to celebrate her last wedding anniversary. She smiled from a face that was as radiant as an angel's.

"I told my friends that I was going to go out with my son, and they were impressed," she said, as she got into the car. "They can't wait to hear about our meeting". We went to a restaurant that, although not elegant, was very nice and cozy. My mother took my arm as if she were the First Lady.

After we sat down, I had to read the menu to her. Her eyes could only read large print. Half way through the entree, I lifted my eyes and saw Mom sitting there staring at me.

A nostalgic smile was on her lips. "It was I who used to have to read the menu when you were small," she said.

"Then it's time for you to relax and let me return the favor," I responded.

During the dinner we had an agreeable conversation, nothing extraordinary - but catching up on recent events of each others lives. We talked so much that we missed the movie.

As we arrived at her house later, she said "I'll go out with you again, but only if you let me invite you". I agreed.

"How was your dinner date?" asked my wife when I got home. "Very nice. Much more so than I could have imagined," I answered.

A few days later my mother died of a massive heart attack. It happened so suddenly that I didn't have a chance to do anything for her.

Some time later I received an envelope with a copy of a restaurant receipt from the same place mother and I had dined.

An attached note said: "I paid this bill in advance. I was almost sure that I couldn't be there but, nevertheless, I paid for two plates - one for you and the other for your wife. You will never know what that night meant to me. I love you."

At that moment I understood the importance of saying, in time: "I LOVE YOU" and giving our loved ones the time that they deserve.

Nothing in life is more important than God and your family and friends.

Give them the time they deserve, because these things cannot be put off till "some other time".

Someone once said "I've learned that, regardless of your relationship with your parents, you'll miss them when they're gone from your life.

I think this is true with your in-laws, grandchildren, sisters, brothers and your friends. Anyone that means something to you-you should spend time with them and let them know how much they mean to you as often as you can.

To love and to be loved is everything.